Chronic Diseases Prevention Review (Online ISSN: 2158-0820)

by  Na Li, Yuan Liu, Wenhao Yan, Xin Sui, Hui Li, Xiaohua Li, Xiaozheng Shi, 

      Qing Yang, Jiaming Sun, Xingcheng Lan, Xijun Chen, Xiaobo Qu, Jianan Lin, Dianjun Sui

Chronic Diseases Prevention Review 2018 2(8) 1-4; published online 25 August  2018

Abstract:  Aging is a serious problem which is challenging the entire human race. With the longer life of people, more and more people are suffering from Alzheimer’s disease (AD), which is suffering from not only for the patients themselves but also for the society. To be the king herb of Traditional Chinese Medicine (TCM), ginseng had been used as a treatment for dementia with a long history. Based on the traditional effect of “Reinforcing Intelligence” of ginseng, we reorganized the literatures and references about ginseng on the treatment of AD.

by Haoyue Ding, Yingfen Hu, Li Ma, Yanyan Li, Xin Liang

Chronic Diseases Prevention Review 2018 2(8) 5-12; published online 25 August 2018

Abstract: The total flavone content and antioxidant activities of EtOH, EtOAc, BuOH and water extracts of the Dongzao jujube (Zizyphus jujuba Mill. cv. Dongzao) were measured. Total flavone content was assessed by the spectrophotometry whereas antioxidant activities were assessed by measuring the ability of the extracts to scavenge the DPPH•, hydroxyl radicals and superoxide anion radicals, the ability to reduce ferric ions as well as inhibition capability of lipid peroxidation and erythrocyte hemolysis. The results indicated that all the extracts had activity dose-dependent in DPPH radical, superoxide anion radical, hydroxyl radical scavenging systems and reducing power activity assay. Among these assays, the scavenging activities on superoxide anion and hydroxyl radicals of the ethanolic extract were slightly lower than those of ascorbic acid, but higher than those of tertiary butylhydroquinone (TBHQ). The ethanolic extracts showed strong antioxidant activity against the lipid peroxidation and antihemolytic activity. These results suggested that the extracts from Dongzao jujube have direct and potent antioxidant activity. It might be used as a potential plant source of antioxidants. The Dongzao jujube extract contains 3',4',7-Trihydroxyisoflavone, 4',6,7-Trihydroxyisoflavone, luteolin, 5,7-Dihydroxy flavonoids, etc.